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Erythema Migrans Rash
The majority of cases of Lyme disease start with a bull's eye rash ("erythema chronicum migrans") at the site of the tick bite. The rash can occur days to weeks (typically 7-10 days) after a tick bite.
Treatment with antibiotics is indicated if this rash appears.
It is thought that Lyme Disease can be prevented if the tick is removed within 24 hours of attachment.
Source: CDC PHIL
From the CDC's Public Health Image Library (http://phil.cdc.gov), ID#9875, in the public domain.