FDA advises against Pap test as primary cervical cancer detection

FDA advises against Pap test as primary cervical cancer detection

Until recently, the leading method of detecting cervical cancer was the Pap test. Now, the Food and Drug Administration (FDA) is advising against the 60-year-old method and pushing for a more modern human papillomavirus (HPV) testing.

The new test, backed by the FDA, is called the Roche test. This method detects the actual DNA of HPV, whereas the traditional pap searched for particular shaped cells which might indicate cancer. Both tests are administered with a vaginal swab.

The FDA says the Roche test is better for detection as it can discover two different strains of HPV, which are responsible for more than 70 percent of cervical cancers.

The FDA advisory committee voted, and the Roche test will replace the Pap test as the primary standard of testing for women over 25 years of age. Though the FDA does not have to follow the recommendations of this committee, in this case, it did.

“Cervical cancer in women is a largely preventable disease. Knowing that the new test provides a better chance of catching HPV, which is responsible for most cases, is exciting for the future of cancer detection,” says Dr. Yvonne Collins, gynecological oncologist with Advocate Medical Group in Oak Lawn, Ill.

Physicians use the two tests in tandem, also called co-testing, in order to achieve the best possible outcome for detecting HPV and cervical cancer, especially in women over 30.

With the HPV test being made the first-line of detection, experts say that many patients will still rely on their practitioners to explain why these changes are being made and how they will affect their health.

HPV testing is a better predictor of disease,” Dr. Collins says. “Starting detection with the HPV test will eliminate further unnecessary testing for patients.”

Related Posts



  1. I don’t think you can treat HPV, but you can treat abnormally shaped cells by using cryosurgery, etc. The article says the Roche test would replace the PAP, but later says physicians use both tests. If the DNA test reveals HPV, is it also showing if the cells are something that needs to be treated?

  2. I think they mean that the Roche test will be used in addition to the PAP to detect cervical cancer. Traditionally only the PAP test was used to look for cervical cancer.

Subscribe to health enews newsletter

About the Author

health enews Staff
health enews Staff

health enews staff is a group of experienced writers from our Advocate Health Care and Aurora Health Care sites, which also includes freelance or intern writers.